Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.85 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.85 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031092 | 0.86 | F2 (1.00) | F2PRSS1F10KDM4EMEN1 | |
| SCHEMBL8035205 | 0.85 | F2 (0.62) | F2PRSS1ALDH1A1TACR1 | |
| SCHEMBL7396115 | 0.83 | F2 (0.73) | F2PRSS1F10KDM4EMEN1 | |
| SCHEMBL7367313 | 0.82 | F2 (1.00) | F2PRSS1F10KDM4EMEN1 | |
| SCHEMBL7367315 | 0.82 | F2 (1.00) | F2PRSS1F10KDM4EMEN1 | |
| SCHEMBL8029406 | 0.80 | F2 (0.72) | F2PRSS1F10KDM4EALDH1A1 | |
| SCHEMBL7363325 | 0.78 | F2 (0.58) | F2PRSS1F10KDM4EMEN1 | |
| SCHEMBL7365097 | 0.76 | F2 (1.00) | F2PRSS1F10RAB9A | |
| SCHEMBL7367913 | 0.74 | F2 (1.00) | F2PRSS1F10ALDH1A1 | |
| SCHEMBL7364521 | 0.73 | F2 (0.86) | F2PRSS1F10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0960102-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | Du Pont Pharmaceuticals Company (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5886191-A | ANTICOAGULANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| WO-1998001428-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-01-15 | — | — | WO | disclosed |