Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PPID | Q08752 | 3/20 | 0.34 |
| ▸ | PPIG | Q13427 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433790 | 0.93 | UBE2N (0.38) | NPSR1FNTAFNTBUBE2NPGGT1B | |
| SCHEMBL7433784 | 0.93 | UBE2N (0.38) | NPSR1FNTAFNTBUBE2NPGGT1B | |
| SCHEMBL7281265 | 0.86 | TRHR (0.45) | NPSR1PPIDPPIG | |
| SCHEMBL7279683 | 0.85 | FNTA (0.33) | ALDH1A1FNTAFNTBUBE2NPGGT1B | |
| SCHEMBL7280342 | 0.84 | UBE2N (0.33) | FNTAFNTBUBE2NPGGT1B | |
| SCHEMBL7434279 | 0.81 | TRHR (0.37) | UBE2N | |
| SCHEMBL7434285 | 0.81 | TRHR (0.37) | UBE2N | |
| SCHEMBL7274298 | 0.76 | FNTA (0.34) | ALDH1A1FNTAFNTBUBE2NPGGT1B | |
| SCHEMBL7274290 | 0.76 | FNTA (0.34) | ALDH1A1FNTAFNTBUBE2NPGGT1B | |
| SCHEMBL7273756 | 0.74 | FNTA (0.33) | FNTAFNTBUBE2NPGGT1BPPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |