Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329655 | 0.90 | REN (0.67) | REN | |
| SCHEMBL7429748 | 0.87 | REN (0.60) | REN | |
| SCHEMBL10520738 | 0.87 | PSMB5 (0.61) | REN | |
| SCHEMBL30533376 | 0.86 | REN (0.61) | REN | |
| SCHEMBL7433143 | 0.85 | REN (0.61) | REN | |
| SCHEMBL9725900 | 0.84 | REN (0.61) | REN | |
| SCHEMBL9725895 | 0.84 | REN (0.61) | REN | |
| SCHEMBL10444086 | 0.84 | REN (0.71) | REN | |
| SCHEMBL9725871 | 0.84 | REN (0.61) | REN | |
| SCHEMBL10444511 | 0.84 | REN (0.71) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4820691-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0296581-A2 | Amino acid 1,2-diketo derivatives as renin inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1988-12-28 | — | — | EP | disclosed |