Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 12/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428216 | 0.96 | CACNA1B (0.58) | CACNA1BADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL10614840 | 0.89 | ABCC1 (0.63) | CACNA1BADORA3ABCC1CACNA1FCACNA1D | |
| SCHEMBL7429597 | 0.89 | CACNA1B (0.58) | CACNA1BADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7438147 | 0.87 | CACNA1B (0.58) | CACNA1BADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7433647 | 0.87 | ADORA3 (0.47) | CACNA1BADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7424120 | 0.87 | CACNA1B (0.57) | CACNA1BADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7431234 | 0.87 | CACNA1B (0.57) | CACNA1BADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7428978 | 0.85 | CACNA1B (0.56) | CACNA1BADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7428763 | 0.84 | CACNA1B (0.55) | CACNA1BADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7435874 | 0.84 | ADORA3 (0.54) | CACNA1BADORA3CACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272693-A2 | New aralkyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1988-06-29 | — | — | EP | claimed |
| US-5075324-A | ARALKYL-1,4-DIHYDROPYRIDINES, A METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1991-12-24 | — | — | US | disclosed |
| EP-0272693-A2 | New aralkyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1988-06-29 | — | — | EP | disclosed |