⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18613979 | 0.91 | CES2 (0.46) | — | |
| SCHEMBL1176708 | 0.88 | CES2 (0.48) | — | |
| SCHEMBL28315654 | 0.88 | CES2 (0.48) | — | |
| SCHEMBL18614056 | 0.88 | CES2 (0.48) | — | |
| SCHEMBL198724 | 0.84 | — | — | |
| SCHEMBL11126902 | 0.77 | CES1 (0.40) | — | |
| SCHEMBL16194365 | 0.77 | — | — | |
| SCHEMBL4633356 | 0.77 | CES1 (0.40) | — | |
| SCHEMBL7955527 | 0.75 | CES1 (0.43) | — | |
| SCHEMBL5967506 | 0.75 | CES1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2920225-B1 | REACTION ACCELERATOR FOR A COPOLYMERISATION , ELECTRICAL-INSULATION TAPE, ELECTRICAL-INSULATION BODY, AND CONSOLIDATION BODY | SIEMENS AG (DE) | 2017-11-29 | — | — | EP | claimed |
| US-20150361103-A1 | REACTION ACCELERATOR FOR A COPOLYMERISATION, ELECTRICAL-INSULATION TAPE, ELECTRICAL-INSULATION BODY, AND CONSOLIDATION BODY | SIEMENS AKTIENGESELLSCHAFT (DE) | 2015-12-17 | — | — | US | claimed |
| EP-2762512-A1 | Reaction accelerator for a copolymerization, electrical insulation tape, electrical insulation body and consolidation body | Siemens Aktiengesellschaft (DE) | 2014-08-06 | — | — | EP | claimed |
| US-20220151992-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (HK) | 2022-05-19 | — | — | US | disclosed |
| US-11077094-B2 | Spiro-lactam NMDA receptor modulators and uses thereof | APTINYX INC. (US) | 2021-08-03 | — | — | US | disclosed |
| US-20200206189-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (HK) | 2020-07-02 | — | — | US | disclosed |
| US-10441571-B2 | Spiro-lactam NMDA receptor modulators and uses thereof | APTINYX INC. (US) | 2019-10-15 | — | — | US | disclosed |
| US-10383877-B2 | Use of substituted 2, 3-dihydroimidazo[1,2-c]quinazolines for the treatment of myeloma | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-08-20 | — | — | US | disclosed |
| CN-109111536-A | Catalytic component and its catalyst for olefinic polymerization | 中国石油化工股份有限公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-109111539-A | Catalytic component and its catalyst for olefinic polymerization | 中国石油化工股份有限公司 | 2019-01-01 | — | — | CN | disclosed |
| US-10087198-B2 | Reaction accelerator for a copolymerisation, electrical-insulation tape, electrical-insulation body, and consolidation body | SIEMENS AKTIENGESELLSCHAFT (DE) | 2018-10-02 | — | — | US | disclosed |
| US-20080286832-A1 | Methods for Obtaining Optically Active Epoxides and Vicinal Diols From 2,2-Disubstituted Epoxides | COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH (ZA) | 2008-11-20 | — | — | US | disclosed |
| US-20080213833-A1 | Methods for Obtaining Optically Active Glycidyl Ethers and Optically Active Vicinal Diols from Racemic Substrates | OXRANE (UK) LTD. (GB) | 2008-09-04 | — | — | US | disclosed |
| US-20080199912-A1 | Methods for Obtaining Optically Active Epoxides and Diols from 2,3-Disubstituted and 2,3-Trisubstituted Epoxides | OXYRANE (UK) LTD. (GB) | 2008-08-21 | — | — | US | disclosed |
| EP-1885849-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE GLYCIDYL ETHERS AND OPTICALLY ACTIVE VICINAL DIOLS FROM RACEMIC SUBSTRATES | Oxyrane UK Limited (GB) | 2008-02-13 | — | — | EP | disclosed |
| US-20070275448-A1 | Methods For Obtaining Optically Active Epoxides And Vicinal Diols From Meso-Epoxides | CSIR (ZA) | 2007-11-29 | — | — | US | disclosed |
| EP-1753862-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM MESO-EPOXIDES | CSIR (ZA) | 2007-02-21 | — | — | EP | disclosed |
| WO-2006109198-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE GLYCIDYL ETHERS AND OPTICALLY ACTIVE VICINAL DIOLS FROM RACEMIC SUBSTRATES | OXYRANE UK LIMITED (GB) | 2006-10-19 | — | — | WO | disclosed |
| WO-2005100578-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM MESO-EPOXIDES | CSIR (ZA) | 2005-10-27 | — | — | WO | disclosed |
| EP-0005504-A1 | Process for the preparation of 5,5-disubstituted-4-ureido-hexahydropyrimidines | BASF Aktiengesellschaft (DE) | 1979-11-28 | — | — | EP | disclosed |