Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CALCA | P06881 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443498 | 0.82 | ITGB3 (0.58) | HRH3KDM4ECYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7435244 | 0.82 | NPY2R (0.52) | PANK3KDM4ECYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7444975 | 0.80 | PANK3 (0.42) | CTSSCTSKPANK3KDM4EALDH1A1 | |
| SCHEMBL7440141 | 0.80 | CHRM2 (0.46) | CTSSCTSKPANK3KDM4EALDH1A1 | |
| SCHEMBL7442787 | 0.80 | KDM4E (0.48) | PANK3KDM4ETP53 | |
| SCHEMBL7337863 | 0.80 | KDM4E (0.46) | CTSSCTSKHRH3PANK3KDM4E | |
| SCHEMBL7444330 | 0.79 | KDM4E (0.48) | KDM4ECYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL7444850 | 0.79 | NPY2R (0.42) | CTSSCTSKHRH3PANK3KDM4E | |
| SCHEMBL7442319 | 0.79 | KDM4E (0.42) | CTSSCTSKPANK3KDM4ECYP2C9 | |
| SCHEMBL7441631 | 0.79 | PANK3 (0.39) | CTSSCTSKPANK3KDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |