Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.55 |
| ▸ | NPY1R | P25929 | 9/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.55 |
| ▸ | NPY2R | P49146 | 5/20 | 0.55 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21570230 | 1.00 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2RENPEP | |
| SCHEMBL7435218 | 1.00 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2RENPEP | |
| SCHEMBL7435448 | 0.91 | LAP3 (0.53) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL21570268 | 0.91 | LAP3 (0.53) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7435439 | 0.91 | LAP3 (0.53) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29674598 | 0.91 | LAP3 (0.53) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL21570265 | 0.91 | FNTA (0.50) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29674608 | 0.91 | FNTA (0.50) | NPY4RNPY1RNPY5RNPY2R | |
| Hydrochloric Acid SCHEMBL7445350 | 0.90 | LAP3 (0.52) | NPY4RNPY1RNPY5RNPY2R | |
| Hydrochloric Acid SCHEMBL7445342 | 0.90 | LAP3 (0.52) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |