Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.63 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.63 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3165934 | 0.84 | TAS1R3 (0.67) | HSP90AA1HSP90AB1 | |
| SCHEMBL14817133 | 0.80 | TAS1R3 (0.76) | HSP90AA1HSP90AB1 | |
| SCHEMBL9732092 | 0.80 | — | — | |
| SCHEMBL2427286 | 0.79 | HSP90AA1 (0.85) | HSP90AA1HSP90AB1 | |
| SCHEMBL2425089 | 0.79 | HSP90AA1 (0.85) | HSP90AA1HSP90AB1 | |
| SCHEMBL2425092 | 0.79 | HSP90AA1 (0.85) | HSP90AA1HSP90AB1 | |
| SCHEMBL2426001 | 0.79 | HSP90AA1 (0.85) | HSP90AA1HSP90AB1 | |
| SCHEMBL2426003 | 0.79 | HSP90AA1 (0.85) | HSP90AA1HSP90AB1 | |
| SCHEMBL2427289 | 0.79 | HSP90AA1 (0.85) | HSP90AA1HSP90AB1 | |
| SCHEMBL2423578 | 0.79 | HSP90AA1 (0.85) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491148-A | TREATING GASTROINTESTINAL, CARDIOVASCULAR, CENTRAL NERVOUS SYSTEM DISORDERS, EMESIS, PAIN | SYNTEX (U.S.A.) INC. (US) | 1996-02-13 | — | — | US | disclosed |