Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 17/20 | 1.00 |
| ▸ | HTR3E | A5X5Y0 | 16/20 | 1.00 |
| ▸ | HTR3B | O95264 | 16/20 | 1.00 |
| ▸ | HTR3D | Q70Z44 | 16/20 | 1.00 |
| ▸ | HTR3C | Q8WXA8 | 16/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436088 | 0.99 | HTR3A (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7433224 | 0.97 | HTR3A (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7443204 | 0.93 | HTR3A (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7429427 | 0.90 | HTR3A (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7442883 | 0.87 | HTR3A (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7434079 | 0.86 | HTR3A (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7444184 | 0.85 | HTR3A (0.79) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL30036625 | 0.85 | HTR3A (0.98) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7439281 | 0.85 | HTR3A (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7435184 | 0.83 | HTR3A (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458636-B1 | Antiemetic and migraine suppressing heterocyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1995-07-12 | — | — | EP | disclosed |