Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433209 | 0.97 | TMEM97 (0.48) | TMEM97SIGMAR1GRIN1GRIN2B | |
| SCHEMBL7956559 | 0.81 | TMEM97 (0.43) | TMEM97SIGMAR1 | |
| SCHEMBL467160 | 0.77 | GRIN1 (0.70) | SIGMAR1GRIN1GRIN2B | |
| SCHEMBL7435401 | 0.76 | TMEM97 (0.54) | TMEM97SIGMAR1GRIN1GRIN2B | |
| SCHEMBL7433042 | 0.76 | GRIN1 (0.56) | GRIN1GRIN2B | |
| SCHEMBL8011281 | 0.76 | TMEM97 (0.53) | TMEM97SIGMAR1GRIN1GRIN2B | |
| SCHEMBL8010301 | 0.76 | GRIN1 (0.68) | GRIN1GRIN2B | |
| SCHEMBL8010239 | 0.76 | GRIN1 (0.68) | GRIN1GRIN2B | |
| SCHEMBL19852344 | 0.75 | SIGMAR1 (0.50) | SIGMAR1 | |
| SCHEMBL8012780 | 0.75 | GRIN1 (0.66) | SIGMAR1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207677-B1 | ADMINISERING SIGMA RECEPTOR BINDING PIPERIDINE DERIVATIVE FOR TREATING ANXIETY, EPILEPSY, CONVULSION, MOVEMENT DISORDER, AMNESIA | H. LUNDBECK A/S (DK) | 2001-03-27 | — | — | US | disclosed |
| EP-0859004-A1 | Piperidine derivatives having anxiolytic effect | H. LUNDBECK A/S (DK) | 1998-08-19 | — | — | EP | disclosed |
| EP-0853085-A1 | Piperidine derivatives having anxiolytic effect | H. LUNDBECK A/S (DK) | 1998-07-15 | — | — | EP | disclosed |
| US-5665725-A | Piperidine derivatives having anxiolytic effect | Lundbeck, H. (DK) | 1997-09-09 | — | — | US | disclosed |
| EP-0518805-A1 | Piperidine derivatives | H. LUNDBECK A/S (DK) | 1992-12-16 | — | — | EP | disclosed |