Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | ACP3 | P15309 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30370514 | 1.00 | TAAR1 (0.58) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL3237564 | 0.94 | TAAR1 (0.64) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL1551304 | 0.86 | LTA4H (0.54) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL30634707 | 0.85 | PPARG (0.53) | TAAR1IDO1ALDH1A1TSHRCALM1 | |
| SCHEMBL4977397 | 0.85 | MAOB (0.62) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL145568 | 0.85 | TAAR1 (0.51) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL9885484 | 0.85 | IDO1 (0.54) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL21165039 | 0.85 | MAPT (0.58) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL30063565 | 0.85 | LTA4H (0.52) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL2721465 | 0.83 | NR4A2 (0.66) | MEN1KMT2AACP3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128337-A | Hypotensive agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-07 | — | — | US | claimed |
| EP-3783434-A1 | PHOTOSENSITIVE COMPOSITION FOR EUV LIGHT, PATTERN FORMATION METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE | FUJIFILM CORPORATION (JP) | 2021-02-24 | — | — | EP | disclosed |
| CN-109641836-A | Fluorinated 2- amino -4- (substituted amino) carbanilate derivative | 赛弗卢尔生命科学公司 | 2019-04-16 | — | — | CN | disclosed |
| US-20130253185-A1 | NOVEL CATALYSTS | DALHOUSIE UNIVERSITY (CA) | 2013-09-26 | — | — | US | disclosed |