Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204874 | 0.85 | CYP2C9 (0.56) | CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL10431513 | 0.78 | CHRM2 (0.39) | RIPK1MEN1KMT2A | |
| SCHEMBL7349406 | 0.77 | CYP2C9 (0.41) | CYP2C9CYP2C19 | |
| SCHEMBL7424303 | 0.77 | CYP2C9 (0.41) | CYP2C9CYP2C19 | |
| SCHEMBL7424298 | 0.77 | CYP2C9 (0.41) | CYP2C9CYP2C19 | |
| SCHEMBL7349416 | 0.77 | CYP2C9 (0.41) | CYP2C9CYP2C19 | |
| SCHEMBL7430706 | 0.77 | CYP2C9 (0.41) | CYP2C9CYP2C19 | |
| SCHEMBL1938131 | 0.74 | CA12 (0.41) | RIPK1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL13501913 | 0.73 | MEN1 (0.56) | CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL3549503 | 0.73 | CYP2C9 (0.61) | CYP2C9CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120728-A1 | Thiazine and thiazepine containing compounds | E.R. Squibb & Sons, Inc. (US) | 1984-10-03 | — | — | EP | disclosed |