Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424298 | 1.00 | CYP2C9 (0.41) | CYP2C9CYP2C19 | |
| SCHEMBL7424303 | 1.00 | CYP2C9 (0.41) | CYP2C9CYP2C19 | |
| SCHEMBL7349416 | 1.00 | CYP2C9 (0.41) | CYP2C9CYP2C19 | |
| SCHEMBL7349406 | 1.00 | CYP2C9 (0.41) | CYP2C9CYP2C19 | |
| SCHEMBL8483604 | 0.84 | ALDH1A1 (0.46) | CYP2C9CYP2C19 | |
| SCHEMBL7344546 | 0.81 | SIGMAR1 (0.36) | — | |
| SCHEMBL7344553 | 0.81 | SIGMAR1 (0.36) | — | |
| SCHEMBL7340298 | 0.79 | CA12 (0.43) | CYP2C9CYP2C19 | |
| SCHEMBL7340501 | 0.79 | CA12 (0.43) | CYP2C9CYP2C19 | |
| SCHEMBL7340287 | 0.79 | CA12 (0.43) | CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711884-A | HYPOTENSIVE AGENTS; ANGIOTENSIN ENZYME INHIBITING ACTIVITY | E. R. SQUIBB & SONS, INC. (US) | 1987-12-08 | — | — | US | disclosed |
| EP-0154904-B1 | ACYLAMINO OXO OR HYDROXY SUBSTITUTED ALKYLAMINO THIAZINES AND THIAZEPINES | E.R. Squibb & Sons, Inc. (US) | 1987-10-28 | — | — | EP | disclosed |
| EP-0154904-A1 | Acylamino oxo or hydroxy substituted alkylamino thiazines and thiazepines | E.R. Squibb & Sons, Inc. (US) | 1985-09-18 | — | — | EP | disclosed |
| US-4512988-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1985-04-23 | — | — | US | disclosed |
| EP-0120728-A1 | Thiazine and thiazepine containing compounds | E.R. Squibb & Sons, Inc. (US) | 1984-10-03 | — | — | EP | disclosed |