Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.59 |
| ▸ | ITGAV | P06756 | 5/20 | 0.49 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435590 | 1.00 | ITGB3 (0.59) | ITGB3ITGA2BITGAVCFDNAMPT | |
| SCHEMBL6677664 | 0.92 | ITGB3 (0.70) | ITGB3ITGA2BITGAV | |
| SCHEMBL6677677 | 0.92 | ITGB3 (0.70) | ITGB3ITGA2BITGAV | |
| SCHEMBL7445376 | 0.89 | ITGB3 (0.54) | ITGB3ITGA2BITGAVNAMPT | |
| SCHEMBL7445367 | 0.89 | ITGB3 (0.54) | ITGB3ITGA2BITGAVNAMPT | |
| SCHEMBL6677682 | 0.89 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL6950146 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL6675230 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL7437125 | 0.84 | ITGB3 (0.68) | ITGB3ITGA2BITGAV | |
| SCHEMBL7437143 | 0.84 | ITGB3 (0.68) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | claimed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | claimed |
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |