Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436450 | 0.82 | TSPO (0.44) | TSHRALDH1A1HSD17B10TDP1KDM4E | |
| SCHEMBL4908178 | 0.76 | KMT2A (0.48) | TSHRALDH1A1HSD17B10MAPK1CYP1A2 | |
| SCHEMBL29387070 | 0.76 | TSHR (0.69) | TSHRALDH1A1HSD17B10MAPK10TDP1 | |
| SCHEMBL180024 | 0.76 | TSHR (0.69) | TSHRALDH1A1HSD17B10MAPK10TDP1 | |
| Diethyl Phthalate SCHEMBL2206814 | 0.75 | TSHR (0.88) | TSHRALDH1A1HSD17B10TDP1MAPK1 | |
| Diethyl Phthalate SCHEMBL28775845 | 0.75 | TSHR (0.95) | TSHRALDH1A1HSD17B10MAPK10TDP1 | |
| Diethyl Phthalate SCHEMBL19252611 | 0.75 | TSHR (0.95) | TSHRALDH1A1HSD17B10MAPK10TDP1 | |
| SCHEMBL5696478 | 0.74 | CDC25B (0.41) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL3454897 | 0.74 | TSHR (0.67) | TSHRALDH1A1HSD17B10MAPK10TDP1 | |
| Ammonia Solution, Strong SCHEMBL10715942 | 0.74 | TSHR (0.67) | TSHRALDH1A1HSD17B10MAPK10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364493-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1990-04-25 | — | — | EP | claimed |
| WO-1989001488-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1989-02-23 | — | — | WO | claimed |
| EP-0364493-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1989001488-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1989-02-23 | — | — | WO | disclosed |