Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426465 | 0.97 | LTA4H (0.55) | LTA4HTACR1TDP1L3MBTL1NPC1 | |
| SCHEMBL7921740 | 0.95 | LTA4H (0.53) | LTA4HTACR1TDP1L3MBTL1NPC1 | |
| SCHEMBL9445833 | 0.95 | LTA4H (0.53) | LTA4HTACR1TDP1L3MBTL1NPC1 | |
| SCHEMBL2420914 | 0.95 | LTA4H (0.53) | LTA4HTACR1TDP1L3MBTL1NPC1 | |
| SCHEMBL7923624 | 0.95 | LTA4H (0.53) | LTA4HTACR1TDP1L3MBTL1NPC1 | |
| SCHEMBL13109616 | 0.95 | LTA4H (0.53) | LTA4HTACR1TDP1L3MBTL1NPC1 | |
| SCHEMBL13997528 | 0.94 | LTA4H (0.51) | LTA4HTACR1TDP1L3MBTL1NPC1 | |
| SCHEMBL15953973 | 0.90 | IDO1 (0.52) | TACR1NPC1RAB9AIDO1AGXT | |
| SCHEMBL13109617 | 0.88 | LTA4H (0.46) | LTA4HTACR1TDP1L3MBTL1NPC1 | |
| SCHEMBL13997516 | 0.88 | LTA4H (0.46) | LTA4HTACR1TDP1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520372-B1 | Inositol phosphate analogues as calcium-antagonistic substances | HOECHST AG (DE) | 1996-12-04 | — | — | EP | disclosed |
| US-5395828-A | Cardiovascular | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0520372-A1 | Inositol phosphate analogues as calcium-antagonistic substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-30 | — | — | EP | disclosed |