Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435809 | 1.00 | ALOX15 (0.40) | ALOX15CYP1A2CYP2D6CYP2C19SLC1A3 | |
| SCHEMBL21896074 | 0.84 | CYP2D6 (0.47) | ALOX15CYP1A2CYP2D6CYP2C19SLC1A3 | |
| SCHEMBL7340980 | 0.84 | CYP2D6 (0.47) | ALOX15CYP1A2CYP2D6CYP2C19SLC1A3 | |
| SCHEMBL9297990 | 0.84 | CYP2D6 (0.47) | ALOX15CYP1A2CYP2D6CYP2C19SLC1A3 | |
| SCHEMBL3450013 | 0.84 | CYP2D6 (0.47) | ALOX15CYP1A2CYP2D6CYP2C19SLC1A3 | |
| SCHEMBL3771173 | 0.84 | CYP2D6 (0.47) | ALOX15CYP1A2CYP2D6CYP2C19SLC1A3 | |
| SCHEMBL3450012 | 0.84 | CYP2D6 (0.47) | ALOX15CYP1A2CYP2D6CYP2C19SLC1A3 | |
| Hydrochloric Acid SCHEMBL17600576 | 0.82 | CYP1A2 (0.46) | ALOX15CYP1A2CYP2D6CYP2C19SLC1A3 | |
| Hydrochloric Acid SCHEMBL16288453 | 0.82 | CYP1A2 (0.46) | ALOX15CYP1A2CYP2D6CYP2C19SLC1A3 | |
| Hydrochloric Acid SCHEMBL16287994 | 0.82 | CYP1A2 (0.46) | ALOX15CYP1A2CYP2D6CYP2C19SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |