Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 4/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.35 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449578 | 0.92 | ITGB3 (0.51) | NPY2RITGB3ITGA2BALOX15ESR1 | |
| SCHEMBL7449550 | 0.89 | ITGB3 (0.42) | NPY2RITGB3ITGA2BALOX15KDM4E | |
| SCHEMBL7435464 | 0.89 | ITGB3 (0.53) | NPY2RITGB3ITGA2BALOX15ESR1 | |
| Hydrogen Sulfide SCHEMBL7442224 | 0.88 | NPY2R (0.50) | NPY2RITGB3ITGA2BALOX15KDM4E | |
| SCHEMBL7444850 | 0.84 | NPY2R (0.42) | NPY2RESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL7444145 | 0.84 | ITGB3 (0.53) | NPY2RITGB3ITGA2BALOX15KDM4E | |
| SCHEMBL7437083 | 0.84 | ITGB3 (0.41) | NPY2RITGB3ITGA2BALOX15KDM4E | |
| SCHEMBL7443152 | 0.83 | NPY2R (0.50) | NPY2RITGB3ITGA2BALOX15KDM4E | |
| SCHEMBL7436252 | 0.82 | NPY2R (0.49) | NPY2RITGB3ITGA2BALOX15KDM4E | |
| SCHEMBL7436257 | 0.82 | NPY2R (0.49) | NPY2RITGB3ITGA2BALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |