Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427089 | 1.00 | MAPT (0.51) | MAPTLMNACYP1A1CYP1B1HPGD | |
| SCHEMBL5723172 | 0.80 | MAPT (0.56) | MAPTLMNACYP1A1CYP1B1HPGD | |
| SCHEMBL5723162 | 0.80 | MAPT (0.56) | MAPTLMNACYP1A1CYP1B1HPGD | |
| SCHEMBL6953461 | 0.80 | PDE4D (0.43) | LMNACYP1B1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7439473 | 0.79 | PDE4D (0.43) | MAPTLMNASMN1; SMN2ALDH1A1PDE4D | |
| SCHEMBL7439466 | 0.79 | PDE4D (0.43) | MAPTLMNASMN1; SMN2ALDH1A1PDE4D | |
| SCHEMBL7439470 | 0.79 | PDE4D (0.43) | MAPTLMNASMN1; SMN2ALDH1A1PDE4D | |
| SCHEMBL7435793 | 0.78 | MAPT (0.60) | MAPTLMNACYP1A1CYP1B1HPGD | |
| SCHEMBL7435790 | 0.78 | MAPT (0.60) | MAPTLMNACYP1A1CYP1B1HPGD | |
| SCHEMBL7444318 | 0.76 | PDE4D (0.46) | PDE4DPDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819688-A1 | 4-substituted benzofuranes | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1998-01-21 | — | — | EP | disclosed |