Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435793 | 1.00 | MAPT (0.60) | MAPTLMNACYP1A1CYP1B1HPGD | |
| SCHEMBL5723162 | 0.82 | MAPT (0.56) | MAPTLMNACYP1A1CYP1B1HPGD | |
| SCHEMBL5723172 | 0.82 | MAPT (0.56) | MAPTLMNACYP1A1CYP1B1HPGD | |
| SCHEMBL5723270 | 0.80 | MAPT (0.60) | MAPTLMNACYP1A1CYP1B1HPGD | |
| SCHEMBL5723273 | 0.80 | MAPT (0.60) | MAPTLMNACYP1A1CYP1B1HPGD | |
| Hydrochloric Acid SCHEMBL5723058 | 0.79 | MAPT (0.58) | MAPTLMNACYP1A1CYP1B1HPGD | |
| Hydrochloric Acid SCHEMBL5723047 | 0.79 | MAPT (0.58) | MAPTLMNACYP1A1CYP1B1HPGD | |
| SCHEMBL7427089 | 0.78 | MAPT (0.51) | MAPTLMNACYP1A1CYP1B1HPGD | |
| SCHEMBL7435873 | 0.78 | MAPT (0.51) | MAPTLMNACYP1A1CYP1B1HPGD | |
| SCHEMBL6950787 | 0.77 | ALDH1A1 (0.42) | MAPTLMNAHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819688-A1 | 4-substituted benzofuranes | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1998-01-21 | — | — | EP | disclosed |