Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10726945 | 0.84 | HPGD (0.35) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL10724226 | 0.83 | CTSL (0.40) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL3174465 | 0.82 | HPGD (0.37) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL22263552 | 0.79 | HRH3 (0.37) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL1505020 | 0.79 | USP2 (0.49) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL7407007 | 0.76 | HPGD (0.37) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL27529379 | 0.76 | MEN1 (0.46) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL79826 | 0.76 | HPGD (0.37) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL1447519 | 0.74 | HPGD (0.39) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL18289862 | 0.74 | HPGD (0.39) | MEN1KMT2AALDH1A1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |