Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 3/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052100 | 0.98 | PDE2A (0.44) | PDE2AADORA3PDE5APDE3BPDE3A | |
| SCHEMBL7436566 | 0.94 | PDE2A (0.45) | PDE2AADORA3PNPLMNAKDM4E | |
| SCHEMBL7502873 | 0.91 | HPGD (0.44) | PDE2AADORA2BLMNAKDM4EPOLB | |
| SCHEMBL7438492 | 0.89 | MEN1 (0.41) | PDE2AKDM4EHPGD | |
| SCHEMBL6051961 | 0.85 | PARP1 (0.47) | PDE2ALMNAKDM4EPOLBALDH1A1 | |
| SCHEMBL6051959 | 0.85 | PDE2A (0.63) | PDE2AADORA3PNPLMNAKDM4E | |
| SCHEMBL8472454 | 0.83 | PDE5A (0.61) | PDE2APDE5ALMNAKDM4EALDH1A1 | |
| SCHEMBL6051956 | 0.82 | PDE2A (0.43) | PDE2APNPLMNAKDM4EPOLB | |
| SCHEMBL6051965 | 0.80 | PDE2A (0.57) | PDE2AADORA3PNPPOLBHPGD | |
| SCHEMBL7436563 | 0.80 | PDE2A (0.57) | PDE2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861404-A | ANTIINFLAMMATORY AGENTS, THROMBOEMBOLIC AND CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | claimed |