Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL135123 | 1.00 | — | — | |
| Ether SCHEMBL8349382 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAHSD17B10THRB | |
| Ether SCHEMBL8119384 | 0.95 | — | — | |
| Ether SCHEMBL28029448 | 0.95 | — | — | |
| Ether SCHEMBL8895591 | 0.95 | — | — | |
| Ether SCHEMBL21903105 | 0.91 | ALDH1A1 (0.44) | ALDH1A1TSHRLMNAHSD17B10THRB | |
| Ether SCHEMBL3925372 | 0.91 | ALDH1A1 (0.44) | ALDH1A1TSHRLMNAHSD17B10 | |
| Ether SCHEMBL4608383 | 0.91 | — | — | |
| Ether SCHEMBL2395413 | 0.91 | — | — | |
| Ether SCHEMBL6248783 | 0.91 | ALDH1A1 (0.53) | ALDH1A1TSHRLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590348-B1 | Central venous catheters loaded with lipodalbaheptide antibiotics preventing development of catheter related infections | AVENTIS BULK S P A (IT) | 2002-02-27 | — | — | EP | disclosed |
| US-5750509-A | TREATMENT AGAINST INFECTIONS BY BACTERIA INCLUDING ENTEROCOCCUS, AND STAPHYLOCOCCUS | GRUPPO LEPETIT S.P.A. (IT) | 1998-05-12 | — | — | US | disclosed |
| EP-0596929-B1 | AMIDE DERIVATIVES OF ANTIBIOTIC A 40926 | LEPETIT SPA (IT) | 1995-07-26 | — | — | EP | disclosed |
| EP-0596929-A1 | AMIDE DERIVATIVES OF ANTIBIOTIC A 40926. | LEPETIT SPA (IT) | 1994-05-18 | — | — | EP | disclosed |
| EP-0590348-A1 | Central venous catheters loaded with lipodalbaheptide antibiotics preventing development of catheter related infections | GRUPPO LEPETIT S.p.A. (IT) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993003060-A1 | AMIDE DERIVATIVES OF ANTIBIOTIC A 40926 | GRUPPO LEPETIT S.P.A. (IT) | 1993-02-18 | — | — | WO | disclosed |
| EP-0525499-A1 | Amide derivatives of antibiotic A 40926 | GRUPPO LEPETIT S.p.A. (IT) | 1993-02-03 | — | — | EP | disclosed |