Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRK2 | P25098 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294900 | 1.00 | QDPR (0.39) | QDPRMEN1POLBGAAKMT2A | |
| SCHEMBL7436138 | 1.00 | QDPR (0.39) | QDPRMEN1POLBGAAKMT2A | |
| SCHEMBL7430268 | 0.84 | PARP1 (0.44) | QDPRMEN1POLBGAAKMT2A | |
| SCHEMBL7302987 | 0.84 | PARP1 (0.44) | QDPRMEN1POLBGAAKMT2A | |
| SCHEMBL7430243 | 0.84 | PARP1 (0.44) | QDPRMEN1POLBGAAKMT2A | |
| SCHEMBL7431434 | 0.82 | PARP1 (0.36) | QDPRMEN1POLBGAAKMT2A | |
| SCHEMBL7431416 | 0.82 | PARP1 (0.36) | QDPRMEN1POLBGAAKMT2A | |
| SCHEMBL7431423 | 0.82 | PARP1 (0.36) | QDPRMEN1POLBGAAKMT2A | |
| Bromide SCHEMBL9150727 | 0.81 | PARP1 (0.36) | QDPRMEN1POLBGAAKMT2A | |
| Bromide SCHEMBL9150707 | 0.81 | PARP1 (0.36) | QDPRMEN1POLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381235-B1 | PYRROLIDINE COMPOUND AND PHARMACEUTICAL USE | Eisai Co., Ltd. (JP) | 1993-07-28 | — | — | EP | disclosed |