Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219953 | 0.85 | GRM2 (0.53) | ALDH1A1TAAR1TDP1SLC13A5GRM2 | |
| SCHEMBL11088109 | 0.85 | GRM2 (0.53) | ALDH1A1TAAR1TDP1SLC13A5GRM2 | |
| SCHEMBL7441576 | 0.85 | GRM2 (0.53) | ALDH1A1TAAR1TDP1SLC13A5GRM2 | |
| SCHEMBL28966331 | 0.81 | BLM (0.65) | BLMCA2CAMK2AESR1ESR2 | |
| SCHEMBL17768418 | 0.81 | BLM (0.65) | BLMCA2CAMK2AESR1ESR2 | |
| SCHEMBL31563005 | 0.80 | BLM (0.69) | BLMCA2CAMK2AESR1ESR2 | |
| SCHEMBL30407061 | 0.80 | GRM2 (0.59) | TAAR1CTBP2GRM2GRM3 | |
| SCHEMBL25596779 | 0.77 | BLM (0.47) | BLMCA2CAMK2AESR1ESR2 | |
| SCHEMBL22033166 | 0.77 | BLM (0.47) | BLMCA2CAMK2AESR1ESR2 | |
| SCHEMBL27550853 | 0.73 | BLM (0.50) | BLMCA2CAMK2AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | claimed |