Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 6/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17768418 | 1.00 | BLM (0.65) | BLMCA2CAMK2ASMN1; SMN2HIF1A | |
| SCHEMBL2336417 | 0.83 | SMN1; SMN2 (0.67) | BLMSMN1; SMN2HIF1AMEN1CYP1A2 | |
| SCHEMBL17498702 | 0.83 | SMN1; SMN2 (0.67) | BLMSMN1; SMN2HIF1AMEN1CYP1A2 | |
| SCHEMBL16816903 | 0.83 | SMN1; SMN2 (0.67) | BLMSMN1; SMN2HIF1AMEN1CYP1A2 | |
| SCHEMBL7387615 | 0.82 | BLM (0.67) | BLMCA2CAMK2ASMN1; SMN2HIF1A | |
| SCHEMBL7436157 | 0.81 | BLM (0.51) | BLMCA2CAMK2AFNTAFNTB | |
| SCHEMBL24253146 | 0.78 | BLM (0.62) | BLMCA2CAMK2ASMN1; SMN2HIF1A | |
| SCHEMBL20292653 | 0.78 | BLM (0.62) | BLMCA2CAMK2ASMN1; SMN2HIF1A | |
| SCHEMBL17768416 | 0.78 | BLM (0.62) | BLMCA2CAMK2ASMN1; SMN2HIF1A | |
| Racemetyrosine SCHEMBL61871 | 0.78 | BLM (1.00) | BLMCA2CAMK2ASMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605493-A | Prodrugs of4'-C-substituted-2-halo-2' -deoxyadenosine nucleosides and methods of making and using the same | 吉利德科学公司（US） | 2023-01-13 | — | — | CN | disclosed |