SCHEMBL7436200

SCHEMBL7436200

Cc1c(C)c2ccc(OCc3ccc(C#N)cc3)cc2oc1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOB P27338 16/20 1.00
ACHE P22303 9/20 0.83
MAOA P21397 6/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5618607 0.87 MAOB (1.00) MAOBACHEMAOA
SCHEMBL7436182 0.87 MAOB (1.00) MAOBACHEMAOA
SCHEMBL5617511 0.86 MAOB (0.82) MAOBACHEMAOA
SCHEMBL7432466 0.85 MAOB (1.00) MAOBACHEMAOA
SCHEMBL7436425 0.85 MAOB (0.82) MAOBACHEMAOA
SCHEMBL7423689 0.85 MAOB (1.00) MAOBACHEMAOA
SCHEMBL7432074 0.84 ACHE (1.00) MAOBACHEMAOA
SCHEMBL7301269 0.83 ACHE (0.78) MAOBACHEMAOA
SCHEMBL5618032 0.82 MAOB (0.77) MAOBACHEMAOA
SCHEMBL5618504 0.82 MAOB (0.77) MAOBACHEMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0363793-B1 ARYL ALKOXY COUMARINS, PROCESS FOR THEIR PRODUCTION AND THERAPEUTIC AGENTS CONTAINING THEM BASF Aktiengesellschaft (DE) 1993-04-21 EP disclosed
US-5100914-A Monoamine Oxidase Inhibitors, Central Nervous System Disorders BASF AKTIENGESELLSCHAFT (DE) 1992-03-31 US disclosed
EP-0363793-A1 Aryl alkoxy coumarins, process for their production and therapeutic agents containing them BASF Aktiengesellschaft (DE) 1990-04-18 EP disclosed