Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311878 | 0.81 | KMT2A (0.46) | KMT2AGSK3BPTPN1GPR139MAPT | |
| SCHEMBL9301261 | 0.79 | KMT2A (0.44) | KMT2AGSK3BPTPN1GPR139MAPT | |
| SCHEMBL19619388 | 0.75 | MAPT (0.52) | KMT2AGSK3BPTPN1MAPTTDP1 | |
| SCHEMBL3754394 | 0.75 | MAPT (0.52) | KMT2AGSK3BPTPN1MAPTTDP1 | |
| SCHEMBL17236360 | 0.74 | KMT2A (0.46) | KMT2AGSK3BPTPN1GPR139MAPT | |
| SCHEMBL1641518 | 0.74 | HDAC3 (0.55) | KMT2AGSK3BPTPN1GPR139MAPT | |
| SCHEMBL18113289 | 0.74 | POLB (0.46) | KMT2AMAPTTDP1MAPK1MEN1 | |
| SCHEMBL16047247 | 0.73 | KMT2A (0.52) | KMT2AGSK3BPTPN1GPR139MAPT | |
| Hydrochloric Acid SCHEMBL10431496 | 0.73 | MAPT (0.50) | KMT2AGSK3BPTPN1MAPTTDP1 | |
| SCHEMBL17236362 | 0.73 | KMT2A (0.45) | KMT2AGSK3BPTPN1GPR139MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |