Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19619388 | 1.00 | MAPT (0.52) | MAPTKMT2ATDP1CYP3A4MAPK1 | |
| Hydrochloric Acid SCHEMBL10431496 | 0.98 | MAPT (0.50) | MAPTKMT2ATDP1CYP3A4MAPK1 | |
| SCHEMBL3242580 | 0.83 | MAPT (0.56) | MAPTKMT2ATDP1CYP3A4MAPK1 | |
| SCHEMBL23064499 | 0.82 | MAPT (0.50) | MAPTKMT2ATDP1CYP3A4MAPK1 | |
| SCHEMBL95591 | 0.81 | KMT2A (0.54) | MAPTKMT2ATDP1CYP3A4MAPK1 | |
| SCHEMBL95590 | 0.81 | MAPT (0.54) | MAPTKMT2ATDP1CYP3A4MAPK1 | |
| SCHEMBL379725 | 0.81 | KMT2A (0.54) | MAPTKMT2ATDP1CYP3A4MAPK1 | |
| SCHEMBL7793888 | 0.80 | MAPT (0.33) | MAPTKMT2ATDP1CYP3A4MAPK1 | |
| SCHEMBL11115633 | 0.80 | NPC1 (0.52) | MAPTKMT2AMEN1HPGDSMN1; SMN2 | |
| Methylamine SCHEMBL13837152 | 0.80 | MAPT (0.48) | MAPTKMT2ATDP1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213254-B | Beta-nitroketone and preparation method and application method thereof | 北京师范大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-114213254-A | Beta-nitroketone, and preparation method and application method thereof | 北京师范大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-109143778-A | Resin combination, cured film, the manufacturing method of colour filter and cured film | 东京应化工业株式会社 | 2019-01-04 | — | — | CN | disclosed |
| CN-108957956-A | Solidification compound, solidfied material, cured film, the manufacturing method of display panel and solidfied material | 东京应化工业株式会社 | 2018-12-07 | — | — | CN | disclosed |
| US-20100292289-A1 | TREATMENT OF METABOLIC SYNDROME WITH NOVEL AMIDES | AMPLA PHARMACEUTICALS INC. (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292289-A1 | TREATMENT OF METABOLIC SYNDROME WITH NOVEL AMIDES | AMPLA PHARMACEUTICALS INC. (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292289-A1 | TREATMENT OF METABOLIC SYNDROME WITH NOVEL AMIDES | AMPLA PHARMACEUTICALS INC. (US) | 2010-11-18 | — | — | US | disclosed |
| WO-2009073138-A2 | TREATMENT OF METABOLIC SYNDROME WITH NOVEL AMIDES | AMPLA PHARMACEUTICALS INC. (US) | 2009-06-11 | — | — | WO | disclosed |
| EP-0153890-A2 | Derivatives of 3-phenyl-2-propenamine, their preparation and medicines containing them | RHONE-POULENC SANTE (FR) | 1985-09-04 | — | — | EP | disclosed |
| US-4273851-A | Method of coating using photopolymerizable latex systems | RICHARDSON GRAPHICS COMPANY (US) | 1981-06-16 | — | — | US | disclosed |
| US-4224398-A | Photopolymerizable latex systems | RICHARDSON GRAPHICS COMPANY (US) | 1980-09-23 | — | — | US | disclosed |
| US-4186069-A | PARTICLES OF WATER-INSOLUBLE POLYMERS IN COMBINATION WITH WATER-SOLUBLE, LIGHT-SENSITIVE POLYMERS | RICHARDSON GRAPHICS COMPANY (US) | 1980-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292289-A1 | TREATMENT OF METABOLIC SYNDROME WITH NOVEL AMIDES | GPR119, CPT1A, GLS2 | MAPT 3155/4885KMT2A 1826/4885TDP1 4666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.