Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.76 |
| ▸ | TUBB | P07437 | 3/20 | 0.76 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.76 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.76 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.76 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.76 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.76 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.76 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.76 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.76 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.76 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.76 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.76 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.76 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.76 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29689431 | 0.92 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL20696534 | 0.92 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30869991 | 0.90 | ATM (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10343404 | 0.90 | ATM (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL23913120 | 0.88 | ATM (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31556190 | 0.88 | ATM (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31556187 | 0.88 | ATM (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7424861 | 0.88 | HTR2A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3872175 | 0.83 | PPARG (0.62) | ATMKDM4ECYP19A1CA2POLB | |
| SCHEMBL9301138 | 0.83 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321135-A | Process for the preparation of polycyclic compounds using ferric perchlorate and acid trifluoroacidic | TSUMURA & CO. (JP) | 1994-06-14 | — | — | US | disclosed |
| EP-0594890-A1 | Polycyclic compounds, their preparation and their use as phosphodiesterases inhibitors | TSUMURA & CO. (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0511666-A1 | Process for the preparation of polycyclic compounds | TSUMURA & CO. (JP) | 1992-11-04 | — | — | EP | disclosed |