Stearic Acid

Stearic Acid

SCHEMBL743675

CCCCCCCCCCCCCCCCCC(=O)O.O=C(O)CCC(=O)O

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.94
PPARG P37231 7/20 0.94
PPARD Q03181 7/20 0.94
PPARA Q07869 7/20 0.94
HDAC11 Q96DB2 5/20 0.94
TSHR P16473 4/20 0.94
PTPN1 P18031 3/20 0.94
FABP4 P15090 3/20 0.94
ALDH1A1 P00352 2/20 0.94
TLR2 O60603 2/20 0.94
TDP1 Q9NUW8 2/20 0.94
KMT2A Q03164 2/20 0.94
ALOX15 P16050 2/20 0.94
HSD17B10 Q99714 2/20 0.94
SLC22A6 Q4U2R8 1/20 0.94
SLC22A8 Q8TCC7 1/20 0.94
MEN1 O00255 1/20 0.94
ESR1 P03372 1/20 0.94
PDE4A P27815 1/20 0.94
PDE3A Q14432 1/20 0.94

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dodecanoate SCHEMBL28005537 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL8641216 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Heptanoate SCHEMBL28513064 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL27093015 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL20994175 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL1659991 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Hexacosanoic Acid SCHEMBL25287701 0.97 GPR84 (1.00) GPR84PPARGPPARDPPARAHDAC11
Lignoceric Acid SCHEMBL25290912 0.97 GPR84 (1.00) GPR84PPARGPPARDPPARAHDAC11
Myristic Acid SCHEMBL23705769 0.97 GPR84 (1.00) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL25286532 0.97 GPR84 (1.00) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115887253-A Ethyl ferulate-loaded squalane-based nano lipid carrier and preparation method and application thereof 华南理工大学 2023-04-04 CN claimed
WO-2024204667-A1 FOOD PRODUCT INCLUDING VIABLE CELLS OF LACTIC ACID BACTERIA, METHOD FOR PRODUCING SAME, AND METHOD FOR INHIBITING INCREASE IN ACIDITY AND/OR DECREASE IN NUMBER OF VIABLE CELLS 三菱ケミカル株式会社 2024-10-03 WO disclosed
CN-115887253-A Ethyl ferulate-loaded squalane-based nano lipid carrier and preparation method and application thereof 华南理工大学 2023-04-04 CN disclosed
CN-113845946-A Fuel additive, preparation method thereof and fuel composition 中国石油化工股份有限公司 2021-12-28 CN disclosed
EP-3697775-A1 RET9 AND VEGFR2 INHIBITORS Kala Pharmaceuticals, Inc. (US) 2020-08-26 EP disclosed
EP-3487945-A1 USE OF POLYOLESTERS FOR PRODUCING POROUS PLASTIC COATINGS Evonik Degussa GmbH (DE) 2019-05-29 EP disclosed
WO-2019079747-A1 RET9 AND VEGFR2 INHIBITORS KALA PHARMACEUTICALS, INC. (US) 2019-04-25 WO disclosed
EP-2489653-B1 METHOD FOR PRODUCING REDUCED COENZYME Q10 AND COMPOSITION COMPRISING SAME KANEKA CORP (JP) 2017-11-29 EP disclosed
US-9040747-B2 Method for producing reduced coenzyme Q10, method for stabilizing same, and composition comprising same KANEKA CORPORATION (JP) 2015-05-26 US disclosed
US-8496968-B2 Method for production of microcapsules using solid fat KANEKA CORPORATION (JP) 2013-07-30 US disclosed
US-20120207731-A1 METHOD FOR PRODUCING REDUCED COENZYME Q10, METHOD FOR STABILIZING SAME, AND COMPOSITION COMPRISING SAME KANEKA CORPORATION (JP) 2012-08-16 US disclosed
EP-2430011-A1 5-PYRIDIN-3-YL-1,3-DIHYDRO-INDOL-2-ON DERIVATIVES AND THEIR USE AS MODULATORS OF ALDOSTERONE SYNTHASE AND/OR CYP11B1 Novartis AG (CH) 2012-03-21 EP disclosed
US-20110091553-A1 METHOD FOR PRODUCING MICROCAPSULES USING SOLID FAT KANEKA CORPORATION (JP) 2011-04-21 US disclosed
US-20100297222-A1 METHOD FOR PRODUCTION OF MICROCAPSULES USING SOLID FAT KANEKA CORPORATION (JP) 2010-11-25 US disclosed
WO-2010130794-A1 5-PYRIDIN-3-YL-1,3-DIHYDRO-INDOL-2-ON DERIVATIVES AND THEIR USE AS MODULATORS OF ALDOSTERONE SYNTHASE AND/OR CYP11B1 NOVARTIS AG (CH) 2010-11-18 WO disclosed
EP-2218446-A1 METHOD FOR PRODUCING MICROCAPSULE USING SOLID FAT Kaneka Corporation (JP) 2010-08-18 EP disclosed
US-20100168249-A1 COMPOSITION CONTAINING REDUCED COENZYME Q10, AND METHOD FOR STABILIZING THE COMPOSITION KANEKA CORPORATION (JP) 2010-07-01 US disclosed
CN-1444582-A Heterocyclic compound, their preparation and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-09-24 CN disclosed
WO-1996022270-A1 BIOPOLYMERS DERIVED FROM HYDROLYZABLE DIACID FATS YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1996-07-25 WO disclosed
EP-0388319-A1 Material for food and method for production thereof TERUMO KABUSHIKI KAISHA (JP) 1990-09-19 EP disclosed