Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437000 | 1.00 | GAA (0.42) | GAATDP1MAPTPOLBNPSR1 | |
| SCHEMBL8430019 | 0.84 | TAS1R3 (0.44) | GAAPOLBMGAMSIMGAM2 | |
| SCHEMBL27922427 | 0.82 | NPSR1 (0.46) | GAATDP1MAPTPOLBNPSR1 | |
| SCHEMBL27922423 | 0.82 | NPSR1 (0.46) | GAATDP1MAPTPOLBNPSR1 | |
| SCHEMBL7431545 | 0.81 | TDP1 (0.44) | GAATDP1MAPTPOLBNPSR1 | |
| SCHEMBL29196459 | 0.81 | NPSR1 (0.43) | GAATDP1MAPTPOLBNPSR1 | |
| SCHEMBL29196456 | 0.81 | NPSR1 (0.43) | GAATDP1MAPTPOLBNPSR1 | |
| SCHEMBL7432140 | 0.81 | GAA (0.42) | GAAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7432135 | 0.81 | GAA (0.42) | GAAMAPTCYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL320059 | 0.81 | NPSR1 (0.45) | GAATDP1MAPTPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |