Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.62 |
| ▸ | HTR3A | P46098 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437131 | 1.00 | CHRNA7 (0.62) | CHRNA7HTR3AKCNH2 | |
| Hydrochloric Acid SCHEMBL7432786 | 0.99 | CHRNA7 (0.61) | CHRNA7HTR3AKCNH2 | |
| Hydrochloric Acid SCHEMBL7432776 | 0.99 | CHRNA7 (0.61) | CHRNA7HTR3AKCNH2 | |
| SCHEMBL2228214 | 0.89 | CHRNA7 (0.64) | CHRNA7HTR3AKCNH2 | |
| SCHEMBL7281094 | 0.89 | CHRNA7 (0.64) | CHRNA7HTR3AKCNH2 | |
| SCHEMBL2228215 | 0.89 | CHRNA7 (0.64) | CHRNA7HTR3AKCNH2 | |
| SCHEMBL7438921 | 0.85 | TAS1R3 (0.59) | — | |
| SCHEMBL9597487 | 0.85 | CHRNA7 (0.67) | CHRNA7HTR3A | |
| SCHEMBL7438929 | 0.85 | TAS1R3 (0.59) | — | |
| Hydrochloric Acid SCHEMBL7432766 | 0.84 | TAS1R3 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491148-A | TREATING GASTROINTESTINAL, CARDIOVASCULAR, CENTRAL NERVOUS SYSTEM DISORDERS, EMESIS, PAIN | SYNTEX (U.S.A.) INC. (US) | 1996-02-13 | — | — | US | disclosed |