Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | USP5 | P45974 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421323 | 0.90 | KMT2A (0.50) | MEN1KMT2ANPC1RAB9ASLC5A7 | |
| SCHEMBL2425264 | 0.90 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AMAPK9 | |
| SCHEMBL4965488 | 0.89 | MEN1 (0.42) | MEN1KMT2ANPC1RAB9AMAPK9 | |
| SCHEMBL4197508 | 0.86 | MAPT (0.34) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL2422166 | 0.86 | CYP1A2 (0.49) | MEN1KMT2AMAPK9MAPK10CYP1A2 | |
| SCHEMBL6021869 | 0.85 | MAPK1 (0.42) | MEN1KMT2ANPC1ALDH1A1GAA | |
| SCHEMBL2422967 | 0.83 | MEN1 (0.51) | MEN1KMT2AMAPK9MAPK10ALDH1A1 | |
| SCHEMBL2419313 | 0.83 | MEN1 (0.49) | MEN1KMT2AMAPK9MAPK10ALDH1A1 | |
| SCHEMBL2422241 | 0.82 | MEN1 (0.49) | MEN1KMT2AMAPK9MAPK10FFAR1 | |
| SCHEMBL2425351 | 0.81 | MEN1 (0.49) | MEN1KMT2AMAPK9MAPK10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | claimed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | claimed |