Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443445 | 0.91 | ALDH1A1 (0.46) | MAPK1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2421323 | 0.89 | KMT2A (0.50) | MAPK1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2419841 | 0.89 | MAPK1 (0.49) | MAPK1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4197508 | 0.88 | MAPT (0.34) | MAPK1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2419313 | 0.87 | MEN1 (0.49) | MAPK1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7437261 | 0.85 | MEN1 (0.43) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL2425264 | 0.83 | MEN1 (0.51) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL4965488 | 0.83 | MEN1 (0.42) | KMT2AMEN1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2425351 | 0.83 | MEN1 (0.49) | MAPK1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3480013 | 0.83 | MAPT (0.50) | MAPK1KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663193-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | Applied Research Systems ARS Holding N.V. (AN) | 2006-06-07 | — | — | EP | claimed |
| WO-2005025558-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | APPLIED RESERACH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | claimed |