Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3175852 | 0.86 | CYP1A2 (0.49) | TDP1MEN1KMT2AGAAPOLB | |
| SCHEMBL23685298 | 0.85 | TDP1 (0.51) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL18161573 | 0.84 | ABCB1 (0.58) | MAPT | |
| SCHEMBL31758256 | 0.80 | TDP1 (0.61) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL22381487 | 0.80 | MAOA (0.64) | TDP1MEN1KMT2AGAANPSR1 | |
| SCHEMBL25455532 | 0.80 | KMT2A (0.56) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL12972616 | 0.80 | MAOA (0.45) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL11251419 | 0.80 | MEN1 (0.54) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL26789202 | 0.79 | MEN1 (0.52) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL24712285 | 0.79 | MEN1 (0.47) | TDP1ATMMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |