Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.65 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.65 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498606 | 0.95 | ELANE (0.59) | ELANECTRB1HCRTR1RAB9AALDH1A1 | |
| SCHEMBL7438567 | 0.91 | ELANE (0.63) | ELANECTRB1CTSSCTSLCTSB | |
| SCHEMBL6496223 | 0.89 | ELANE (0.72) | ELANECTRB1CTSSCTSLCTSB | |
| SCHEMBL7444283 | 0.89 | ELANE (0.51) | ELANECTRB1HCRTR1CTSSCTSL | |
| SCHEMBL7447037 | 0.88 | CTRB1 (0.52) | ELANECTRB1HTT | |
| SCHEMBL7837321 | 0.88 | ELANE (0.70) | ELANECTRB1RAB9AALDH1A1LMNA | |
| SCHEMBL6637727 | 0.88 | ELANE (0.57) | ELANECTRB1RAB9AALDH1A1 | |
| SCHEMBL6637731 | 0.88 | ELANE (0.57) | ELANECTRB1RAB9AALDH1A1 | |
| SCHEMBL7838623 | 0.86 | CTRB1 (0.50) | ELANECTRB1RAB9A | |
| SCHEMBL6497427 | 0.85 | ELANE (0.47) | ELANECTRB1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | claimed |
| EP-1122245-A2 | 2-Amino-benzoxazinones for the treatment of viral infections | G.D. Searle & Co. (US) | 2001-08-08 | — | — | EP | disclosed |
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | disclosed |