Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2896418 | 0.90 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8783129 | 0.84 | PKM (0.43) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL4746056 | 0.84 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL18430092 | 0.81 | PKM (0.43) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1091517 | 0.81 | GAA (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL6860553 | 0.79 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11372433 | 0.78 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL23561304 | 0.75 | GAA (0.65) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL19661149 | 0.75 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL18593098 | 0.74 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |