SCHEMBL7437460

SCHEMBL7437460

COC(=O)COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(COC(=O)c1c(Cl)cccc1Cl)C2=O

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7279352 0.91 ELANE (0.74) ELANE
SCHEMBL7281561 0.90 ELANE (0.84) ELANE
SCHEMBL7280505 0.89 ELANE (0.72) ELANE
SCHEMBL7434313 0.89 ELANE (1.00) ELANE
SCHEMBL7282216 0.88 ELANE (0.80) ELANE
SCHEMBL7436728 0.87 ELANE (0.84) ELANE
SCHEMBL7435595 0.86 ELANE (0.78) ELANE
SCHEMBL8865763 0.86 ELANE (0.77) ELANE
SCHEMBL7430748 0.86 ELANE (0.77) ELANE
SCHEMBL7281002 0.85 ELANE (0.76) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5512589-A TREATING DEGENERATIVE DISEASES STERLING WINTHROP INC. (US) 1996-04-30 US claimed
EP-0483928-A1 2-Saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use STERLING WINTHROP INC. (US) 1992-05-06 EP claimed