Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.47 |
| ▸ | CTSL | P07711 | 11/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896670 | 0.81 | CTSS (0.54) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3902120 | 0.78 | CTSS (0.57) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6563875 | 0.77 | CTSS (0.50) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6565450 | 0.76 | CTSS (0.47) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3894558 | 0.75 | CTSS (0.43) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6563724 | 0.73 | CTSS (0.48) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3907528 | 0.71 | CTSS (0.51) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3037914 | 0.71 | CTSS (0.63) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3027455 | 0.70 | CTSS (0.68) | CTSSCTSLCTSKCTSB | |
| SCHEMBL4505588 | 0.70 | CTSS (0.60) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100849-A2 | NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | claimed |