Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.44 |
| ▸ | CTSS | P25774 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 4/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438051 | 0.86 | CA1 (0.41) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL7448767 | 0.84 | CTSK (0.43) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL7435300 | 0.82 | TDP1 (0.42) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL7438236 | 0.80 | CA1 (0.45) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL7445788 | 0.80 | CA1 (0.45) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL7443440 | 0.79 | CA1 (0.48) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL7430737 | 0.79 | CA1 (0.40) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL7444118 | 0.77 | CA1 (0.47) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL7427920 | 0.77 | CTSK (0.47) | CTSKCTSSCA2CAPN1CTSL | |
| SCHEMBL7434049 | 0.76 | CA1 (0.46) | CTSKCTSSCA2CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |