Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437830 | 1.00 | KMT2A (0.56) | KMT2AMEN1NPSR1SMN1; SMN2MMP8 | |
| SCHEMBL7287136 | 0.89 | KMT2A (0.58) | KMT2AMEN1NPSR1SMN1; SMN2MMP8 | |
| SCHEMBL7287129 | 0.89 | KMT2A (0.58) | KMT2AMEN1NPSR1SMN1; SMN2MMP8 | |
| SCHEMBL9355043 | 0.85 | KMT2A (0.53) | KMT2AMEN1NPSR1SMN1; SMN2MMP8 | |
| SCHEMBL9358799 | 0.85 | KMT2A (0.67) | KMT2AMEN1NPSR1SMN1; SMN2MMP8 | |
| SCHEMBL7326296 | 0.85 | KMT2A (0.67) | KMT2AMEN1NPSR1SMN1; SMN2MMP8 | |
| SCHEMBL9355033 | 0.85 | KMT2A (0.53) | KMT2AMEN1NPSR1SMN1; SMN2MMP8 | |
| SCHEMBL7290435 | 0.85 | KMT2A (0.56) | KMT2AMEN1NPSR1SMN1; SMN2MMP8 | |
| SCHEMBL7290442 | 0.85 | KMT2A (0.56) | KMT2AMEN1NPSR1SMN1; SMN2MMP8 | |
| SCHEMBL9800484 | 0.82 | KMT2A (0.59) | KMT2AMEN1NPSR1SMN1; SMN2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |