Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSH | P09668 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800577 | 0.85 | HPGD (0.52) | KMT2AMEN1NPSR1NPC1SMN1; SMN2 | |
| SCHEMBL7287136 | 0.84 | KMT2A (0.58) | KMT2AMEN1NPSR1MMP8TP53 | |
| SCHEMBL7287129 | 0.84 | KMT2A (0.58) | KMT2AMEN1NPSR1MMP8TP53 | |
| SCHEMBL7287305 | 0.83 | KMT2A (0.57) | KMT2AMEN1NPSR1MMP8TP53 | |
| SCHEMBL7290435 | 0.83 | KMT2A (0.56) | KMT2AMEN1NPSR1MMP8TP53 | |
| SCHEMBL7290442 | 0.83 | KMT2A (0.56) | KMT2AMEN1NPSR1MMP8TP53 | |
| SCHEMBL7437832 | 0.82 | KMT2A (0.56) | KMT2AMEN1NPSR1MMP8TP53 | |
| SCHEMBL7437830 | 0.82 | KMT2A (0.56) | KMT2AMEN1NPSR1MMP8TP53 | |
| SCHEMBL7326296 | 0.80 | KMT2A (0.67) | KMT2AMEN1NPSR1MMP8TP53 | |
| SCHEMBL9355043 | 0.80 | KMT2A (0.53) | KMT2AMEN1NPSR1MMP8TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |