Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CPA1 | P15085 | 6/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141466 | 0.86 | CYP1A2 (0.67) | CPA1ANPEPERAP2ERAP1MEN1 | |
| SCHEMBL7434987 | 0.86 | CYP1A2 (0.66) | CPA1CYP1A2 | |
| SCHEMBL10436410 | 0.81 | CPA1 (0.57) | ALDH1A1CPA1ANPEPERAP2ERAP1 | |
| SCHEMBL8531397 | 0.81 | CYP1A2 (0.54) | ALDH1A1CPA1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL7426898 | 0.78 | ANPEP (0.46) | CPA1ANPEPERAP2ERAP1ACE | |
| SCHEMBL5695662 | 0.78 | ACE (0.55) | ALDH1A1GAAACEMEN1KMT2A | |
| SCHEMBL7310938 | 0.78 | ACE (0.55) | ALDH1A1GAAACEMEN1KMT2A | |
| SCHEMBL5418068 | 0.78 | CYP1A2 (0.55) | CPA1ACECYP1A2CYP2C19 | |
| SCHEMBL11123380 | 0.76 | CPA1 (0.62) | ALDH1A1CPA1ANPEPERAP2ERAP1 | |
| SCHEMBL27682962 | 0.74 | CYP1A2 (0.50) | CPA1ACECYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |