SCHEMBL7434987

SCHEMBL7434987

O=C(O)C(CSCc1ccccc1)Cc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.66
CPA1 P15085 4/20 0.58
CPA3 P15088 3/20 0.58
FOLH1 Q04609 2/20 0.58
CPB1 P15086 1/20 0.58
CPB2 Q96IY4 1/20 0.58
SLC1A3 P43003 1/20 0.53
SLC1A2 P43004 1/20 0.53
SLC1A1 P43005 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8531397 0.91 CYP1A2 (0.54) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL5418068 0.91 CYP1A2 (0.55) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL7437992 0.86 ALDH1A1 (0.54) CYP1A2CPA1
SCHEMBL27682962 0.86 CYP1A2 (0.50) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL8500824 0.84 CYP1A2 (0.53) CYP1A2CPA1CPA3
SCHEMBL7273483 0.84 CYP1A2 (0.63) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL8500821 0.84 CYP1A2 (0.53) CYP1A2CPA1CPA3
SCHEMBL7273492 0.84 CYP1A2 (0.63) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL162841 0.81 CYP1A2 (0.70) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL7053102 0.81 CPA3 (0.63) CYP1A2CPA1CPA3FOLH1CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1682702-A Method for preparing pharmaceutical composition capable of inhibiting postinfectious viral protease ALBERT LAB (US) 2005-10-19 CN disclosed
CN-1253019-A Method for preparing pharmaceutical composition capable of inhibiting postinfectious viral protease ALBERT LAB (US) 2000-05-17 CN disclosed
EP-0640594-A1 Hydantoin derivative as metalloprotease inhibitor FUJIREBIO INC. (JP) 1995-03-01 EP disclosed