Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.69 |
| ▸ | FNTA | P49354 | 6/20 | 0.58 |
| ▸ | FNTB | P49356 | 6/20 | 0.58 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.58 |
| ▸ | MME | P08473 | 1/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11389773 | 1.00 | LTA4H (0.69) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7322641 | 0.91 | MME (0.57) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7322646 | 0.91 | MME (0.57) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7328108 | 0.90 | MME (0.59) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7328105 | 0.90 | MME (0.59) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7328102 | 0.90 | MME (0.59) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7440318 | 0.89 | LTA4H (0.66) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7440316 | 0.89 | LTA4H (0.66) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7431726 | 0.88 | LTA4H (0.56) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL6199749 | 0.88 | CYP1A2 (0.58) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262436-A | Administering; enzyme inhibitor | SCHERING CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| US-5061710-A | Atrial natriuretic factors | SCHERING CORPORATION (US) | 1991-10-29 | — | — | US | disclosed |
| US-4929641-A | DIURETICS, ANGIOTENSIN CONVERTING ENZYMES | SCHERING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |