Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426068 | 1.00 | LTA4H (0.49) | LTA4HALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL2744115 | 0.93 | BCHE (0.44) | LTA4HALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL7434030 | 0.93 | BCHE (0.44) | LTA4HALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL2744036 | 0.93 | BCHE (0.44) | LTA4HALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL6373110 | 0.93 | BCHE (0.44) | LTA4HALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL7432416 | 0.93 | BCHE (0.44) | LTA4HALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL2744377 | 0.93 | BCHE (0.44) | LTA4HALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL9456323 | 0.87 | PDPK1 (0.50) | ALDH1A1CYP3A4ALOX15TSHRTACR1 | |
| SCHEMBL13996383 | 0.87 | PDPK1 (0.50) | ALDH1A1CYP3A4ALOX15TSHRTACR1 | |
| SCHEMBL20197126 | 0.87 | PDPK1 (0.50) | ALDH1A1CYP3A4ALOX15TSHRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520372-B1 | Inositol phosphate analogues as calcium-antagonistic substances | HOECHST AG (DE) | 1996-12-04 | — | — | EP | disclosed |
| US-5395828-A | Cardiovascular | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0520372-A1 | Inositol phosphate analogues as calcium-antagonistic substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-30 | — | — | EP | disclosed |