Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426654 | 0.84 | CYP2D6 (0.41) | CA2CA12CA14CYP2D6DGAT1 | |
| SCHEMBL7426659 | 0.84 | CYP2D6 (0.41) | CA2CA12CA14CYP2D6DGAT1 | |
| SCHEMBL18362416 | 0.81 | CYP2D6 (0.37) | CA2CA12CA14CYP2D6DGAT1 | |
| SCHEMBL15180390 | 0.79 | CYP2D6 (0.42) | CA2CA12CA14CYP2D6DGAT1 | |
| SCHEMBL7438213 | 0.79 | CYP1A2 (0.37) | CYP2D6TSHRCTSKMGAMGAA | |
| SCHEMBL8861992 | 0.78 | TSHR (0.36) | CA2CA12CA14CYP2D6DGAT1 | |
| SCHEMBL18428106 | 0.76 | CYP2D6 (0.55) | CA2CA12CA14CYP2D6HDAC3 | |
| SCHEMBL1508734 | 0.76 | CYP2D6 (0.42) | CA2CA12CA14CYP2D6DGAT1 | |
| SCHEMBL4408873 | 0.76 | CYP2D6 (0.50) | CA2CA12CA14CYP2D6CTSK | |
| SCHEMBL8751934 | 0.75 | CYP2D6 (0.36) | CA2CYP2D6PTPRCHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |