Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18362416 | 0.85 | CYP2D6 (0.37) | CA12CA2CA14CA1PTPRC | |
| SCHEMBL2323213 | 0.79 | CA2 (0.41) | TSHRCA12CA2CA14CA1 | |
| SCHEMBL6917401 | 0.79 | CA2 (0.41) | TSHRCA12CA2CA14CA1 | |
| SCHEMBL385450 | 0.79 | CA2 (0.41) | TSHRCA12CA2CA14CA1 | |
| SCHEMBL7438199 | 0.78 | CA2 (0.40) | TSHRCA12CA2CA14CA1 | |
| SCHEMBL7428145 | 0.78 | CA12 (0.37) | TSHRCA12CA2CA14CA1 | |
| SCHEMBL7434264 | 0.78 | CA12 (0.37) | TSHRCA12CA2CA14CA1 | |
| SCHEMBL20786413 | 0.76 | CYP2D6 (0.38) | CA12CA2CA14CA1CYP2D6 | |
| SCHEMBL2104058 | 0.74 | CYP2D6 (0.45) | CA2CA1CYP2D6MEN1KMT2A | |
| SCHEMBL4671387 | 0.74 | CYP2D6 (0.45) | CA2CA1CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5606028-A | Anchimeric radiometal chelating compounds | NEORX CORPORATION (US) | 1997-02-25 | — | — | US | disclosed |
| US-5202451-A | ANCHIMERIC RADIOMETAL CHELATING COMPOUNDS | NEORX CORPORATION (US) | 1993-04-13 | — | — | US | disclosed |