Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 8/20 | 0.51 |
| ▸ | CA2 | P00918 | 8/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438401 | 0.86 | KDM4E (0.53) | PTPN1CA1CA2HSD17B10CA9 | |
| SCHEMBL14954265 | 0.82 | PTPN1 (0.68) | LCKFYNPTPN1CA1CA2 | |
| SCHEMBL30740970 | 0.79 | LCK (0.56) | LCKFYNPTPN1CA1CA2 | |
| SCHEMBL437132 | 0.79 | LCK (0.56) | LCKFYNPTPN1CA1CA2 | |
| SCHEMBL4302772 | 0.78 | LCK (0.59) | LCKFYNPTPN1PKMHSD17B10 | |
| SCHEMBL11541569 | 0.78 | PKM (0.50) | LCKFYNPTPN1PKMHSD17B10 | |
| SCHEMBL4551834 | 0.76 | PKM (0.54) | LCKFYNPKMHSD17B10ALDH1A1 | |
| SCHEMBL12497067 | 0.76 | LCK (0.56) | LCKFYNPTPN1PKMHSD17B10 | |
| SCHEMBL18280365 | 0.74 | MAPT (0.56) | LCKFYNCA1CA2HSD17B10 | |
| SCHEMBL7348961 | 0.74 | MAPT (0.60) | LCKFYNCA1CA2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429987-A2 | AMIDE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Korea Research Institute Of Chemical Technology (KR) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010131922-A2 | AMIDE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-11-18 | — | — | WO | disclosed |